SCHEMBL25155152

SCHEMBL25155152

Cc1cc2cc(CN)[nH]c2cc1C(=O)NC1(c2ccccc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 0.43
KLK1 P06870 1/20 0.43
SLC6A9 P48067 2/20 0.39
TACR3 P29371 2/20 0.39
LOXL2 Q9Y4K0 2/20 0.38
IDO1 P14902 1/20 0.37
TTK P33981 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PDE2A O00408 7/20 0.36
CXCR3 P49682 1/20 0.36
F9 P00740 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25155948 0.94 KLKB1 (0.47) KLKB1KLK1SLC6A9TACR3LOXL2
SCHEMBL25155149 0.90 KLKB1 (0.39) KLKB1KLK1LOXL2PDE2AF9
SCHEMBL31360332 0.90 KLKB1 (0.39) KLKB1KLK1LOXL2PDE2AF9
SCHEMBL25155354 0.89 IDO1 (0.39) KLKB1KLK1SLC6A9LOXL2IDO1
SCHEMBL31359826 0.89 IDO1 (0.39) KLKB1KLK1SLC6A9LOXL2IDO1
SCHEMBL30344712 0.85 LOXL2 (0.37) KLKB1KLK1LOXL2
SCHEMBL25155246 0.85 LOXL2 (0.37) KLKB1KLK1LOXL2
SCHEMBL25155255 0.82 NPC1 (0.38) KLKB1KLK1SLC6A9TACR3PDE2A
SCHEMBL25155732 0.77 MTNR1A (0.34) KLKB1KLK1NPC1RAB9A
SCHEMBL31360248 0.77 MTNR1A (0.34) KLKB1KLK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD KLKB1 584/4885KLK1 396/4885SLC6A9 2377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.