Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31360270 | 1.00 | PPIA (0.36) | PPIAPDK2HDAC8ADAM17KIT | |
| SCHEMBL30344073 | 0.87 | PDK2 (0.49) | PDK2NQO2 | |
| SCHEMBL25155491 | 0.87 | PDK2 (0.49) | PDK2NQO2 | |
| SCHEMBL30344861 | 0.87 | CNR1 (0.34) | — | |
| SCHEMBL25156200 | 0.86 | PDK2 (0.35) | PDK2HDAC8ACACBNQO2ACACA | |
| SCHEMBL25155179 | 0.86 | PDK2 (0.47) | PDK2NQO2 | |
| SCHEMBL30344413 | 0.86 | PDK2 (0.35) | PDK2HDAC8ACACBNQO2ACACA | |
| SCHEMBL30344922 | 0.86 | PDK2 (0.47) | PDK2NQO2 | |
| SCHEMBL25156189 | 0.85 | CTSS (0.35) | PDK2HDAC8 | |
| SCHEMBL30343806 | 0.85 | CTSS (0.35) | PDK2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |