Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 15/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554469 | 0.81 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL8554626 | 0.78 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL8553235 | 0.78 | IRAK4 (0.39) | IRAK4PARP10 | |
| Hydrochloric Acid SCHEMBL7417419 | 0.77 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL25155559 | 0.76 | CHRNB4 (0.50) | IRAK4PARP10 | |
| SCHEMBL8552081 | 0.76 | IRAK4 (0.41) | IRAK4 | |
| SCHEMBL5317949 | 0.74 | PARP10 (0.51) | TDP1PARP10ALDH1A1 | |
| SCHEMBL8554272 | 0.73 | SIRT2 (0.40) | IRAK4 | |
| SCHEMBL8554797 | 0.72 | IRAK4 (0.40) | IRAK4PARP10 | |
| SCHEMBL5749639 | 0.72 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |