Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 15/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7417419 | 0.99 | IRAK4 (0.39) | IRAK4NNMTGSK3BPLAT | |
| SCHEMBL8554469 | 0.87 | IRAK4 (0.40) | IRAK4NNMTGSK3BPLAT | |
| SCHEMBL8553235 | 0.86 | IRAK4 (0.39) | IRAK4GSK3BPLAT | |
| SCHEMBL8507798 | 0.83 | VNN1 (0.31) | IRAK4 | |
| SCHEMBL8552081 | 0.81 | IRAK4 (0.41) | IRAK4 | |
| SCHEMBL8554797 | 0.81 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL8507795 | 0.80 | PIK3CD (0.36) | IRAK4 | |
| Hydrochloric Acid SCHEMBL7413921 | 0.80 | CHRNB2 (0.40) | — | |
| SCHEMBL7409187 | 0.79 | GHSR (0.36) | — | |
| SCHEMBL7414891 | 0.79 | CHRNB2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | disclosed |