Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 15/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554469 | 0.94 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL8554797 | 0.88 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL7816781 | 0.82 | SLC6A2 (0.32) | — | |
| SCHEMBL8553235 | 0.81 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL8554626 | 0.81 | IRAK4 (0.39) | IRAK4 | |
| Hydrochloric Acid SCHEMBL7417419 | 0.81 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL8552096 | 0.80 | SLC6A2 (0.33) | — | |
| SCHEMBL8551354 | 0.79 | CHRNB2 (0.39) | IRAK4KCNH2 | |
| SCHEMBL7827194 | 0.77 | CHRNA3 (0.54) | IRAK4 | |
| SCHEMBL7817793 | 0.77 | CHRNA3 (0.54) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | claimed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | claimed |