SCHEMBL30344830

SCHEMBL30344830

COC(=O)c1cc(OC[C@@H]2CCN2C(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDGFRB P09619 1/20 0.41
▸ FGFR1 P11362 1/20 0.41
▸ PDGFRA P16234 1/20 0.41
▸ FLT1 P17948 1/20 0.41
▸ FGFR3 P22607 1/20 0.41
▸ KDR P35968 1/20 0.41
▸ LMNA P02545 2/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ KMT2A Q03164 3/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ L3MBTL1 Q9Y468 3/20 0.36
▸ UCHL1 P09936 1/20 0.36
▸ USP30 Q70CQ3 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ SIRT6 Q8N6T7 1/20 0.35
▸ MAPT P10636 3/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ EED O75530 1/20 0.35
▸ RBBP4 Q09028 1/20 0.35
▸ SUZ12 Q15022 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30344383 0.91 LMNA (0.37) LMNANPSR1KMT2AMEN1L3MBTL1
SCHEMBL31360255 0.91 LMNA (0.37) LMNANPSR1KMT2AMEN1L3MBTL1
SCHEMBL30344287 0.86 LMNA (0.37) LMNANPSR1KMT2AMEN1L3MBTL1
SCHEMBL25155554 0.85 PDE4A (0.38) LMNANPSR1KMT2AMEN1SMN1; SMN2
SCHEMBL30344487 0.85 PDE4A (0.38) LMNANPSR1KMT2AMEN1SMN1; SMN2
SCHEMBL30344047 0.85 SCN9A (0.45) LMNANPSR1KMT2AMEN1UCHL1
SCHEMBL25156465 0.85 SCN9A (0.45) LMNANPSR1KMT2AMEN1UCHL1
SCHEMBL31615845 0.81 ALDH1A1 (0.48) LMNANPSR1UCHL1USP30SMN1; SMN2
SCHEMBL30344700 0.79 NR1D1 (0.34) LMNANPSR1KMT2AMEN1L3MBTL1
SCHEMBL25155275 0.79 LMNA (0.41) LMNANPSR1KMT2AMEN1EED

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 — — US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD PDGFRB 2156/4885FGFR1 4196/4885PDGFRA 904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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