SCHEMBL2515919

SCHEMBL2515919

CC1CCc2[nH]c3ccccc3c2C1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR2E1 Q9Y466 1/20 0.67
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.54
TP53 P04637 1/20 0.54
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54
RB1 P06400 2/20 0.52
HTR2A P28223 1/20 0.51
HTR2C P28335 1/20 0.51
CHRNA7 P36544 1/20 0.50
DRD1 P21728 2/20 0.49
DRD5 P21918 2/20 0.49
SLC2A1 P11166 1/20 0.49
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
TAAR1 Q96RJ0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7119213 0.89 HPGD (0.68) NR2E1KMT2AMEN1TP53HPGD
SCHEMBL8579183 0.87 RB1 (0.63) NR2E1TP53HPGDHSD17B10RB1
SCHEMBL11076324 0.84 NR2E1 (0.54) NR2E1KMT2AMEN1HPGDHSD17B10
SCHEMBL23875668 0.82 NR2E1 (0.65) NR2E1TP53HPGDHSD17B10RB1
SCHEMBL8528531 0.81 NR2E1 (0.63) NR2E1TP53HPGDHSD17B10RB1
SCHEMBL4288282 0.80 NR2E1 (0.67) NR2E1TP53HPGDHSD17B10RB1
SCHEMBL21900686 0.80 NR2E1 (0.67) NR2E1TP53HPGDHSD17B10RB1
SCHEMBL21754250 0.80 NR2E1 (0.67) NR2E1TP53HPGDHSD17B10RB1
SCHEMBL700531 0.80 NR2E1 (1.00) NR2E1TP53HPGDHSD17B10RB1
SCHEMBL833503 0.80 NR2E1 (1.00) NR2E1TP53HPGDHSD17B10RB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021145729-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2021-07-22 WO disclosed
US-9159929-B2 Rigid amines CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-10-13 US disclosed
US-20130220422-A1 RIGID AMINES CDT OXFORD LIMITED (GB) 2013-08-29 US disclosed
US-8415029-B2 Conjugated polymers prepared from rigid amines CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-04-09 US disclosed
WO-2013012297-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-01-24 WO disclosed
US-8034882-B2 Biscarbazol-9-yl-substituted triarylamine-containing polymers and electronic devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-11 US disclosed
US-20090270414-A1 2,3,4,9- TETRAHYDRO-1H-CARBAZOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD. (CH) 2009-10-29 US disclosed
US-20090206731-A1 Rigid Amines CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2009-08-20 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 US disclosed
WO-2006096399-A2 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES NAT1, SAT1, RIF1 NR2E1 76/4885KMT2A 887/4885MEN1 864/4885
US-20090270414-A1 2,3,4,9- TETRAHYDRO-1H-CARBAZOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS HRH2, CRHR2, GRK2 NR2E1 117/4885KMT2A 3465/4885MEN1 3762/4885
US-20090206731-A1 Rigid Amines PARP3, H1-3, H1-2 NR2E1 407/4885KMT2A 204/4885MEN1 1165/4885
US-20080265755-A1 Biscarbazol-9-Yl-Substituted Triarylamine-Containing Polymers and Electronic Devices PYM1, KCNMB4, BRD9 NR2E1 2449/4885KMT2A 823/4885MEN1 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.