Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 1.00 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | HTR1B | P28222 | 4/20 | 0.59 |
| ▸ | HTR1D | P28221 | 3/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | RB1 | P06400 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700531 | 1.00 | NR2E1 (1.00) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| SCHEMBL29670383 | 1.00 | NR2E1 (1.00) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| SCHEMBL834930 | 1.00 | NR2E1 (1.00) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| Hydrochloric Acid SCHEMBL7412638 | 0.98 | NR2E1 (0.97) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| SCHEMBL29991655 | 0.88 | NR2E1 (0.79) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| SCHEMBL29992005 | 0.88 | NR2E1 (0.79) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| SCHEMBL6533665 | 0.88 | NR2E1 (0.79) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| SCHEMBL4905673 | 0.88 | NR2E1 (0.79) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| Hydrochloric Acid SCHEMBL11283863 | 0.87 | NR2E1 (0.77) | NR2E1HTR6HTR1BHTR1DHTR2A | |
| SCHEMBL8702813 | 0.87 | NR2E1 (0.75) | NR2E1HTR6HTR1BHTR1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586428-A | Biomass-based macromolecular ultraviolet absorber and preparation method and application thereof | 浙江沛格科技有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-104402798-B | A kind of 3-amino-1, the method for splitting of 2,3,4-tetrahydro carbazoles | 杭州瑞德化工有限公司 | 2016-09-14 | — | — | CN | claimed |
| CN-104402798-A | Resolution method for 3-amino-1, 2, 3, 4-tetrahydrocarbazole | HANGZHOU READ CHEMICAL CO LTD | 2015-03-11 | — | — | CN | claimed |
| EP-4710923-A2 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-3612030-B1 | INDOLE AHR INHIBITORS AND USES THEREOF | IKENA ONCOLOGY INC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-04-24 | — | — | US | disclosed |
| US-20250122205-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | PAHR THERAPEUTICS, INC. | 2025-04-17 | — | — | US | disclosed |
| US-12077542-B2 | Indole AHR inhibitors and uses thereof | Ikena Oncology, Inc. (US) | 2024-09-03 | — | — | US | disclosed |
| EP-4396191-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-07-10 | — | — | EP | disclosed |
| CN-118076613-A | Compounds useful for modulating AhR signaling | 捷豹治疗有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117586428-A | Biomass-based macromolecular ultraviolet absorber and preparation method and application thereof | 浙江沛格科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0242518-A1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| CN-87100773-A | Cycloalkanes is [1,2-b] indoles-sulfamide compound also | — | 1987-09-02 | — | — | CN | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | AHR, ARNT, AIPL1 | NR2E1 105/4885HTR6 340/4885HTR1B 693/4885 |
| US-20250122205-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | AHR, ARNT, IDO1 | NR2E1 391/4885HTR6 39/4885HTR1B 76/4885 |
| US-12077542-B2 | Indole AHR inhibitors and uses thereof | AHR, ARNT, IDO1 | NR2E1 391/4885HTR6 39/4885HTR1B 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.