Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538417 | 0.85 | MAPT (0.50) | MAPTPOLBTP53ALDH1A1KMT2A | |
| SCHEMBL20644471 | 0.79 | SMN1; SMN2 (0.36) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL25160177 | 0.76 | TLR7 (0.32) | MAPTTP53TDP1 | |
| SCHEMBL25160444 | 0.70 | PTGS2 (0.35) | ALDH1A1KDM4EHPGD | |
| SCHEMBL25160909 | 0.70 | PTGS2 (0.35) | ALDH1A1KDM4EHPGD | |
| SCHEMBL20644385 | 0.70 | PRMT5 (0.38) | — | |
| SCHEMBL25160112 | 0.69 | RGS4 (0.34) | MAPTPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL20644462 | 0.68 | — | — | |
| SCHEMBL20570136 | 0.68 | TSHR (0.53) | ALDH1A1KMT2AMEN1CYP11B1CYP11B2 | |
| SCHEMBL27383784 | 0.67 | POLB (0.59) | MAPTPOLBTP53ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397629-B1 | METALLOENZYME INHIBITOR COMPOUNDS | NQP 1598 LTD (KY) | 2023-04-19 | — | — | EP | disclosed |