SCHEMBL2516211

SCHEMBL2516211

C=C(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.C=C(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.C=C(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.C=C(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.OCC(CO)(CO)CO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
RECQL P46063 1/20 0.46
ALDH1A1 P00352 5/20 0.42
NPSR1 Q6W5P4 3/20 0.42
MAPK1 P28482 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GABBR2 O75899 2/20 0.42
GABBR1 Q9UBS5 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
TSHR P16473 2/20 0.42
BLM P54132 2/20 0.42
ATM Q13315 2/20 0.42
HIF1A Q16665 2/20 0.42
GMNN O75496 1/20 0.42
TP53 P04637 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
NFKB1 P19838 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9179297 0.90 LMNA (0.50) LMNARECQLALDH1A1NPSR1MEN1
SCHEMBL11510057 0.83 GLRA3 (0.52) LMNARECQLALDH1A1NPSR1MAPK1
SCHEMBL10705030 0.83 GLRA3 (0.52) LMNARECQLALDH1A1NPSR1MAPK1
SCHEMBL28786770 0.81 CYP1A2 (0.50) LMNARECQLALDH1A1NPSR1MEN1
SCHEMBL4196103 0.79 ALDH1A1 (0.47) LMNARECQLALDH1A1NPSR1MAPK1
SCHEMBL28333456 0.75 LMNA (0.49) LMNARECQLALDH1A1NPSR1MEN1
SCHEMBL28183635 0.75 LMNA (0.49) LMNARECQLALDH1A1NPSR1MEN1
SCHEMBL8464404 0.75 GAA (0.43) LMNARECQLALDH1A1NPSR1MAPK1
SCHEMBL28403382 0.74 ALDH1A1 (0.45) LMNARECQLALDH1A1NPSR1MAPK1
SCHEMBL29045735 0.74 ALDH1A1 (0.45) LMNARECQLALDH1A1NPSR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664308-B2 Compatibilizers for producing nanocomposites, microcomposites and polymer blends and process for obtaining them UNIVERSIDAD DE CHILE (CL) 2014-03-04 US claimed
US-8034867-B2 Hybrid clays for obtaining nanocomposites and a preparation process therefore UNIVERSIDAD DE CHILE (CL) 2011-10-11 US claimed
US-20100160509-A1 COMPATIBILIZERS FOR PRODUCING NANOCOMPOSITES, MICROCOMPOSITES AND POLYMER BLENDS AND PROCESS FOR OBTAINING THEM UNIVERSIDAD DE CHILE (CL) 2010-06-24 US claimed
EP-2074156-A1 COMPATIBILIZERS FOR PRODUCING NANOCOMPOSITES, MICROCOMPOSITES AND POLYMER BLENDS AND PROCESS FOR OBTAINING THEM. Universidad De Chile (CL) 2009-07-01 EP claimed
WO-2008044121-A1 COMPATIBILIZERS FOR PRODUCING NANOCOMPOSITES, MICROCOMPOSITES AND POLYMER BLENDS AND PROCESS FOR OBTAINING THEM. UNIVERSIDAD DE CHILE (CL) 2008-04-17 WO claimed
US-20100160509-A1 COMPATIBILIZERS FOR PRODUCING NANOCOMPOSITES, MICROCOMPOSITES AND POLYMER BLENDS AND PROCESS FOR OBTAINING THEM UNIVERSIDAD DE CHILE (CL) 2010-06-24 US disclosed
EP-2074156-A1 COMPATIBILIZERS FOR PRODUCING NANOCOMPOSITES, MICROCOMPOSITES AND POLYMER BLENDS AND PROCESS FOR OBTAINING THEM. Universidad De Chile (CL) 2009-07-01 EP disclosed
WO-2008044121-A1 COMPATIBILIZERS FOR PRODUCING NANOCOMPOSITES, MICROCOMPOSITES AND POLYMER BLENDS AND PROCESS FOR OBTAINING THEM. UNIVERSIDAD DE CHILE (CL) 2008-04-17 WO disclosed