SCHEMBL8464404

SCHEMBL8464404

C=C(C(=O)O)c1ccc(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.43
KMT2A Q03164 5/20 0.43
MEN1 O00255 3/20 0.43
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
BLM P54132 2/20 0.41
ATM Q13315 2/20 0.41
HIF1A Q16665 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
USP2 O75604 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 5/20 0.41
RECQL P46063 1/20 0.40
GABBR2 O75899 2/20 0.40
GABBR1 Q9UBS5 2/20 0.40
GMNN O75496 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9338699 0.81 ALDH1A1 (0.57) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL9179297 0.80 LMNA (0.50) GAAKMT2AMEN1ALDH1A1NPSR1
SCHEMBL1187217 0.76 MEN1 (0.57) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL292110 0.76 ESR1 (0.54) GAAKMT2AMEN1ALDH1A1TSHR
Benzene SCHEMBL9807217 0.76 ALDH1A1 (0.59) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL39559 0.76 ALDH1A1 (0.63) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL8463925 0.75 HSPA5 (0.42) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL5570178 0.75 ALDH1A1 (0.55) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL2516211 0.75 LMNA (0.46) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL526641 0.74 ALDH1A1 (0.61) GAAKMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0796292-B1 STABILIZED STYRENE/BUTADIENE BLOCK COPOLYMERS BASF AG (DE) 1999-05-12 EP disclosed
EP-0806447-A2 Process for the preparation of mixtures of low molecular compounds with polymers BASF AKTIENGESELLSCHAFT (DE) 1997-11-12 EP disclosed
EP-0796292-A1 STABILIZED STYRENE/BUTADIENE BLOCK COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 1997-09-24 EP disclosed
WO-1997000285-A1 STABILISATION OF POLYMERS OF STYRENE OR A (METH)ACRYLIC COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1997-01-03 WO disclosed
WO-1996017886-A1 STABILIZED STYRENE/BUTADIENE BLOCK COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 1996-06-13 WO disclosed