Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829494 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TSHRTHRB | |
| SCHEMBL2515247 | 0.80 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL10064091 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRTHRB | |
| SCHEMBL18400936 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRB | |
| SCHEMBL18850131 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRB | |
| SCHEMBL10150616 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRB | |
| SCHEMBL19718945 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL18400941 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL13790804 | 0.73 | — | — | |
| SCHEMBL22201837 | 0.73 | LTA4H (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283486-B2 | Norbornane skeleton structure-containing organosilicon compound and method of producing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-10-09 | — | — | US | disclosed |
| EP-2450363-A2 | Norbornane skeleton structure-containing organosilicon compound and method of producing same | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-05-09 | — | — | EP | disclosed |
| US-8034965-B2 | Norbornane skeleton structure-containing organosilicon compound and method of producing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-10-11 | — | — | US | disclosed |
| US-20110245525-A1 | NORBORNANE SKELETON STRUCTURE-CONTAINING ORGANOSILICON COMPOUND AND METHOD OF PRODUCING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-10-06 | — | — | US | disclosed |
| US-20090124821-A1 | NORBORNANE SKELETON STRUCTURE-CONTAINING ORGANOSILICON COMPOUND AND METHOD OF PRODUCING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
| EP-2058316-A2 | Norbornane skeleton structure-containing organosilicon compound and method of producing same | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124821-A1 | NORBORNANE SKELETON STRUCTURE-CONTAINING ORGANOSILICON COMPOUND AND METHOD OF PRODUCING SAME | NOTUM, PFAS, WEE1 | ALDH1A1 917/4885TSHR 4844/4885THRB 4556/4885 |
| US-20110245525-A1 | NORBORNANE SKELETON STRUCTURE-CONTAINING ORGANOSILICON COMPOUND AND METHOD OF PRODUCING SAME | NOTUM, PFAS, WEE1 | ALDH1A1 917/4885TSHR 4844/4885THRB 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.