Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248172 | 0.78 | CYP3A4 (0.36) | CYP3A4CYP2D6TSHRCRHBPCYP2C19 | |
| SCHEMBL18307332 | 0.74 | KDM4E (0.43) | KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL31648936 | 0.72 | KMT2A (0.43) | KDM4ELMNACYP3A4CYP2D6TSHR | |
| SCHEMBL30327770 | 0.71 | KDM4E (0.41) | KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL17688749 | 0.71 | HSP90AA1 (0.44) | KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL12848583 | 0.70 | NOS3 (0.34) | — | |
| SCHEMBL24542697 | 0.70 | NOS2 (0.39) | — | |
| SCHEMBL25928386 | 0.68 | — | — | |
| SCHEMBL24457882 | 0.68 | KDM4E (0.39) | KDM4ELMNACYP2C19HSP90AA1HSP90AB1 | |
| SCHEMBL24457884 | 0.68 | KDM4E (0.39) | KDM4ELMNACYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |