Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17816259 | 0.80 | GABRA2 (0.31) | GABRA2GABRB2 | |
| SCHEMBL18307332 | 0.77 | KDM4E (0.43) | KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL21985479 | 0.76 | TRPV4 (0.35) | KDM4ENT5E | |
| SCHEMBL26598284 | 0.74 | NT5E (0.37) | NT5E | |
| SCHEMBL17688749 | 0.74 | HSP90AA1 (0.44) | KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL20349163 | 0.74 | GABRB3 (0.33) | LMNAGABRA2GABRB2 | |
| SCHEMBL22598457 | 0.74 | PDE5A (0.35) | KDM4ELMNA | |
| SCHEMBL11985863 | 0.72 | HSP90AA1 (0.42) | KDM4ELMNAHSP90AA1HSP90AB1NT5E | |
| SCHEMBL20972290 | 0.72 | AR (0.38) | GABRA2GABRB2 | |
| SCHEMBL30636520 | 0.72 | AR (0.38) | GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |