SCHEMBL25166389

SCHEMBL25166389

CSc1nc(NCCN2CCCCC2)nc(SCl)n1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.37
CARM1 Q86X55 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
PRMT8 Q9NR22 1/20 0.36
PLAU P00749 1/20 0.35
TOP2A P11388 1/20 0.35
KAT2B Q92831 1/20 0.35
ACHE P22303 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
SIGMAR1 Q99720 3/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25166626 0.86 HSP90AA1 (0.50) SMN1; SMN2MEN1KMT2ALMNAHSP90AA1
SCHEMBL24831524 0.86 PDE4A (0.44) PIM1CARM1PRMT6PRMT8PLAU
SCHEMBL25166631 0.84 HSD17B10 (0.43) PIM1CARM1PRMT6PRMT8TOP2A
SCHEMBL24831468 0.82 SRC (0.40) KAT2BMEN1KMT2AHSP90AA1SIGMAR1
SCHEMBL24831471 0.80 HSP90AA1 (0.39) SMN1; SMN2MEN1KMT2ALMNAHSP90AA1
SCHEMBL25166403 0.79 HSP90AA1 (0.48) PIM1SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL25166523 0.76 PGK1 (0.40) SMN1; SMN2LMNA
SCHEMBL24831520 0.74 HSD17B10 (0.43) MEN1KMT2ALMNA
SCHEMBL25166627 0.74 LMNA (0.53) SMN1; SMN2MEN1KMT2ALMNAHSP90AA1
SCHEMBL24831574 0.74 SRC (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123334-A1 AMINO LIPID COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Shenzhen Shenxin Biotechnology Co., Ltd. (CN) 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123334-A1 AMINO LIPID COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF CETP, PLIN1, NOTUM PIM1 891/4885CARM1 2798/4885PRMT6 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.