Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 7/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.41 |
| ▸ | CBR1 | P16152 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166808 | 0.93 | MAOA (0.46) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25168019 | 0.89 | AKR1B10 (0.40) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25167167 | 0.87 | NAAA (0.44) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25167885 | 0.85 | AKR1B10 (0.42) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25167999 | 0.85 | AKR1B10 (0.43) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL30422928 | 0.85 | AKR1B10 (0.43) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL30423318 | 0.85 | AKR1B10 (0.43) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25168020 | 0.85 | AKR1B10 (0.43) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL25166772 | 0.84 | NAAA (0.42) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 | |
| SCHEMBL30422923 | 0.84 | NAAA (0.42) | AKR1B10AKR1B1AKR1A1CBR1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |
| WO-2023077162-A2 | METHODS TO QUANTIFY AFFINITY AND SELECTIVITY OF COMPOUNDS FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION (US) | 2023-05-04 | — | — | WO | disclosed |