Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16784068 | 0.90 | GAA (0.53) | GAAMAPTPOLBCASP3CASP7 | |
| SCHEMBL20302878 | 0.88 | GAA (0.66) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL18253238 | 0.87 | POLB (0.52) | GAAMAPTPOLBCASP3CASP7 | |
| SCHEMBL12793245 | 0.77 | POLB (0.88) | GAAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL5307467 | 0.76 | POLB (0.73) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL16735251 | 0.76 | LMNA (0.62) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL1459692 | 0.76 | SMN1; SMN2 (0.71) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL5736053 | 0.76 | POLB (0.58) | GAAMAPTPOLBMEN1KMT2A | |
| SCHEMBL4193606 | 0.76 | TSHR (0.71) | GAAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL5736050 | 0.76 | POLB (0.58) | GAAMAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177246-A1 | FUSED OXAZEPINES AS INHIBITORS OF PEROXIREDOXINS | Centro Atlántico del Medicamento, SA (ES) | 2023-05-10 | — | — | EP | disclosed |
| EP-4177246-A1 | FUSED OXAZEPINES AS INHIBITORS OF PEROXIREDOXINS | Centro Atlántico del Medicamento, SA (ES) | 2023-05-10 | — | — | EP | disclosed |