Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 1.00 |
| ▸ | CA2 | P00918 | 3/20 | 1.00 |
| ▸ | CA9 | Q16790 | 3/20 | 1.00 |
| ▸ | CA12 | O43570 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CKS1B | P61024 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207793 | 1.00 | LMNA (1.00) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL9902123 | 0.95 | LMNA (0.91) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL8659813 | 0.94 | LMNA (0.88) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL5410713 | 0.88 | MCOLN3 (0.78) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL27431915 | 0.87 | LMNA (0.76) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL9901414 | 0.85 | LMNA (0.74) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL11785265 | 0.84 | LMNA (0.77) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL2068526 | 0.84 | LMNA (0.82) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL27826958 | 0.84 | MCOLN3 (0.72) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL23057287 | 0.83 | LMNA (0.71) | LMNAMCOLN3CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004248-B | Method for synthesizing carbazole compound by catalyzing hydrocarbon amination reaction with cobalt | 绍兴文理学院 | 2022-11-18 | — | — | CN | disclosed |
| CN-113004248-A | Method for synthesizing carbazole compound by catalyzing hydrocarbon amination reaction with cobalt | 绍兴文理学院 | 2021-06-22 | — | — | CN | disclosed |
| US-20140088066-A1 | PLATINUM COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | BLEND THERAPEUTICS (US) | 2014-03-27 | — | — | US | disclosed |
| US-8034827-B2 | Phenanthridine derivatives as bradykinin antagonists | Richter Gegeon Nyrt. (HU) | 2011-10-11 | — | — | US | disclosed |
| US-20090270411-A1 | PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2009-10-29 | — | — | US | disclosed |
| EP-1966142-A2 | NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007072092-A2 | NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088066-A1 | PLATINUM COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | APEX1, DPYD, VHL | LMNA 1847/4885MCOLN3 1806/4885CA2 2195/4885 |
| US-20090270411-A1 | PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | BDKRB2, BDKRB1, HRH2 | LMNA 2729/4885MCOLN3 1510/4885CA2 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.