Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.74 |
| ▸ | CA2 | P00918 | 2/20 | 0.74 |
| ▸ | CA9 | Q16790 | 2/20 | 0.74 |
| ▸ | CA12 | O43570 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.72 |
| ▸ | STAT3 | P40763 | 4/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902123 | 0.90 | LMNA (0.91) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL28203701 | 0.85 | LMNA (0.58) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL8659813 | 0.85 | LMNA (0.88) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL31207793 | 0.85 | LMNA (1.00) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL2516997 | 0.85 | LMNA (1.00) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL27431915 | 0.84 | LMNA (0.76) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL7571483 | 0.80 | LMNA (0.67) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL2068526 | 0.79 | LMNA (0.82) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL8663401 | 0.78 | ALDH1A1 (0.74) | LMNAMCOLN3CA2CA9CA12 | |
| SCHEMBL8660547 | 0.78 | LMNA (0.71) | LMNAMCOLN3CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130320269-A1 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | THE UNIVERSITY OF MANCHESTER (GB) | 2013-12-05 | — | — | US | disclosed |
| EP-2649073-A2 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | The University Of Manchester (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076886-A2 | NOVEL PROCESS AND COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-06-14 | — | — | WO | disclosed |