Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tiaramide SCHEMBL25172 | 0.88 | NPY5R (0.58) | TMEM97NPY5RTSHR | |
| Tiaramide SCHEMBL29376518 | 0.88 | NPY5R (0.58) | TMEM97NPY5RTSHR | |
| Tiaramide SCHEMBL181916 | 0.87 | NPY5R (0.58) | TMEM97NPY5RTSHR | |
| Tiaramide SCHEMBL29379184 | 0.87 | NPY5R (0.58) | TMEM97NPY5RTSHR | |
| SCHEMBL27603207 | 0.79 | TMEM97 (0.51) | TMEM97NPY5RALDH1A1HPGDHSD17B10 | |
| SCHEMBL13696444 | 0.78 | NPY5R (0.61) | TMEM97NPY5RTSHR | |
| SCHEMBL11406400 | 0.78 | NPY5R (0.47) | TMEM97NPY5RALDH1A1HPGDHSD17B10 | |
| SCHEMBL8894950 | 0.77 | TMEM97 (0.58) | TMEM97NPY5RCYP3A4CYP2D6OPRK1 | |
| SCHEMBL11343567 | 0.77 | TMEM97 (0.56) | TMEM97NPY5RCYP3A4CYP2D6OPRK1 | |
| SCHEMBL11440143 | 0.76 | TMEM97 (0.47) | TMEM97NPY5RMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56015276-A | — | — | None | — | — | JP | disclosed |
| JP-S5615276-A | PIPERAZINE DERIVATIVE OR ITS SALT, AND ITS PREPARATION | FUJISAWA PHARMACEUT CO LTD | 1981-02-14 | — | — | JP | disclosed |