Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 4/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393323 | 1.00 | KDM4E (0.60) | KDM4EACHEHTR6KMT2AMTNR1A | |
| SCHEMBL24723324 | 0.92 | KDM4E (0.65) | KDM4EACHEHTR6KMT2AMTNR1A | |
| SCHEMBL29992041 | 0.82 | KDM4E (0.73) | KDM4EHTR6KMT2AMTNR1AMTNR1B | |
| SCHEMBL29993218 | 0.82 | KDM4E (0.73) | KDM4EHTR6KMT2AMTNR1AMTNR1B | |
| SCHEMBL24496999 | 0.82 | KDM4E (0.73) | KDM4EHTR6KMT2AMTNR1AMTNR1B | |
| SCHEMBL24723375 | 0.82 | KDM4E (0.66) | KDM4EACHEHTR6KMT2AMTNR1A | |
| SCHEMBL25491588 | 0.81 | ICMT (0.52) | HTR6KMT2AMTNR1AMTNR1BHTR1A | |
| SCHEMBL25169836 | 0.81 | CDK4 (0.61) | KMT2ANPSR1MEN1ALDH1A1RAB9A | |
| SCHEMBL25172585 | 0.79 | HTR6 (0.85) | ACHEHTR6KMT2AMTNR1AMTNR1B | |
| SCHEMBL30370317 | 0.79 | HTR6 (0.85) | ACHEHTR6KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138947-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-20260042735-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC (US) | 2026-02-12 | — | — | US | disclosed |
| US-20240400510-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC (US) | 2024-12-05 | — | — | US | disclosed |
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC. | 2023-05-11 | — | — | US | disclosed |
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC. | 2023-05-11 | — | — | US | disclosed |
| WO-2023070228-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE CANADA INC. (CA) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023070228-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE CANADA INC. (CA) | 2023-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400510-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | HTR2C, HTR2A, HTR3B | KDM4E 2887/4885ACHE 1561/4885HTR6 18/4885 |
| US-20260042735-A1 | BENZYLTRYPTAMINE COMPOUNDS | HTR2C, HTR2A, HTR6 | KDM4E 1324/4885ACHE 1499/4885HTR6 3/4885 |
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | HTR2C, HTR2A, HTR3B | KDM4E 3079/4885ACHE 1410/4885HTR6 17/4885 |
| US-20260138947-A1 | BENZYLTRYPTAMINE COMPOUNDS | HTR2C, CNR2, HTR3B | KDM4E 1924/4885ACHE 2072/4885HTR6 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.