Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 2/20 | 0.43 |
| ▸ | MC3R | P41968 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25649966 | 0.81 | ICMT (0.56) | ICMTNPSR1MEN1KMT2AMTNR1A | |
| SCHEMBL30393323 | 0.81 | KDM4E (0.60) | NPSR1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL25173275 | 0.81 | KDM4E (0.60) | NPSR1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL23127272 | 0.79 | ICMT (0.51) | ICMTNPSR1KMT2AMTNR1AMTNR1B | |
| SCHEMBL24723809 | 0.78 | CDK4 (0.77) | NPSR1CDK4MEN1KMT2ACCND1 | |
| SCHEMBL24723324 | 0.77 | KDM4E (0.65) | CDK4MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL25491586 | 0.77 | HTR6 (0.61) | CDK4KMT2AMTNR1AMTNR1BCCND1 | |
| SCHEMBL25491599 | 0.77 | MEN1 (0.61) | NPSR1CDK4MEN1KMT2ACCND1 | |
| SCHEMBL16494578 | 0.75 | ICMT (0.52) | ICMTNPSR1MEN1KMT2AMTNR1A | |
| SCHEMBL24612547 | 0.75 | TSHR (0.56) | ICMTNPSR1MEN1KMT2ASNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC. | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | HTR2C, HTR2A, HTR3B | ICMT 2739/4885NPSR1 85/4885CDK4 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.