Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25174194 | 1.00 | HCAR3 (0.33) | HCAR3KCNH2IL1B | |
| SCHEMBL22205449 | 0.85 | POLB (0.34) | HCAR3KCNH2IL1B | |
| SCHEMBL20705026 | 0.85 | POLB (0.34) | HCAR3KCNH2IL1B | |
| SCHEMBL22205446 | 0.85 | POLB (0.34) | HCAR3KCNH2IL1B | |
| SCHEMBL22205448 | 0.85 | POLB (0.34) | HCAR3KCNH2IL1B | |
| SCHEMBL23397596 | 0.85 | POLB (0.34) | HCAR3KCNH2IL1B | |
| SCHEMBL25174104 | 0.84 | ALDH1A1 (0.34) | IL1B | |
| SCHEMBL25174105 | 0.79 | — | — | |
| SCHEMBL22214268 | 0.70 | KMT2A (0.38) | — | |
| SCHEMBL23559071 | 0.69 | NAMPT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140983-A1 | PYRIDAZINE DERIVATIVES FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140983-A1 | PYRIDAZINE DERIVATIVES FOR MODULATING NUCLEIC ACID SPLICING | SNRPA, RBM17, SNRPB2 | HCAR3 2840/4885KCNH2 4240/4885IL1B 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.