Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCKDK | O14874 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21612071 | 0.98 | DAO (0.38) | DAOMCL1GPR35TDP1ALDH1A1 | |
| SCHEMBL14463155 | 0.82 | GSK3B (0.31) | DAOGSK3B | |
| Hydrazine SCHEMBL6691493 | 0.79 | MCL1 (0.42) | DAOMCL1GPR35ALDH1A1HPGD | |
| SCHEMBL978687 | 0.78 | MCL1 (0.45) | DAOMCL1GPR35ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7469372 | 0.76 | MCL1 (0.44) | DAOMCL1GPR35ALDH1A1HPGD | |
| SCHEMBL21612064 | 0.75 | KDM4E (0.47) | ALDH1A1HPGDTSHRRXFP1MEN1 | |
| SCHEMBL21612129 | 0.73 | GPR35 (0.46) | DAOMCL1GPR35ALDH1A1HPGD | |
| SCHEMBL21612056 | 0.73 | ALDH1A1 (0.45) | DAOMCL1GPR35ALDH1A1HPGD | |
| SCHEMBL23531564 | 0.73 | MCL1 (0.37) | DAOMCL1GPR35ALDH1A1HPGD | |
| SCHEMBL18701665 | 0.73 | BCKDK (0.41) | DAOMCL1GPR35ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426704-A1 | CONDENSED PYRIDAZINE AMINE DERIVATIVES TREATING SCA3 | Skyhawk Therapeutics, Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| EP-4426702-A1 | CONDENSED-PYRAZINE AMINE DERIVATIVES FOR TREATING SCA3 | Skyhawk Therapeutics, Inc. (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-118496197-A | Substituted thiophenecarboxamides, thiophenecarboxylic acids and derivatives thereof | 拜耳公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114364663-B | Substituted thiophenecarboxamides and derivatives thereof as microbiocides | 拜耳公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023081857-A1 | CONDENSED PYRIDAZINE AMINE DERIVATIVES TREATING SCA3 | SKYHAWK THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081858-A1 | CONDENSED-PYRAZINE AMINE DERIVATIVES FOR TREATING SCA3 | SKYHAWK THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| CN-115103840-A | Substituted thiophenecarboxamides, thiophenecarboxylic acids and derivatives thereof | 拜耳公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3994130-A1 | SUBSTITUTED THIOPHENE CARBOXAMIDES AND DERIVATIVES THEREOF AS MICROBICIDES | Bayer Aktiengesellschaft (DE) | 2022-05-11 | — | — | EP | disclosed |
| CN-114364663-A | Substituted thiophenecarboxamides and derivatives thereof as microbiocides | 拜耳公司 | 2022-04-15 | — | — | CN | disclosed |