SCHEMBL2517875

SCHEMBL2517875

CC(C(=O)O)c1ccccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 1/20 0.52
GAA P10253 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
PTGS2 P35354 4/20 0.47
CXCL8 P10145 1/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP12 P39900 1/20 0.46
MMP13 P45452 1/20 0.46
MMP14 P50281 1/20 0.46
MMP16 P51512 1/20 0.46
PTGS1 P23219 2/20 0.45
CA12 O43570 3/20 0.45
CA1 P00915 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6687220 1.00 ALDH1A1 (0.52) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL21055951 0.90 ALDH1A1 (0.50) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL1344994 0.86 PTGS2 (0.46) ALDH1A1ALOX15MAPTPTGS2CXCL8
SCHEMBL9715714 0.86 ALDH1A1 (0.47) ALDH1A1ALOX15GAAKMT2ATDP1
Hydrogen Peroxide SCHEMBL9514730 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL254364 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL29657201 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
Benzene SCHEMBL28132022 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL134091 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15GAAKMT2ATDP1
SCHEMBL2204495 0.84 PTGS2 (0.56) ALDH1A1KMT2AMAPTPTGS2CXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114727954-A Wet packed soft hydrogel ocular inserts 爱尔康公司 2022-07-08 CN disclosed
CN-109970921-A A kind of high water reduction muting sensitive sense polycarboxylate water-reducer and preparation method thereof 科之杰新材料集团有限公司 2019-07-05 CN disclosed
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-20110247523-A1 ORGANIC-INORGANIC COMPOSITE PARTICLES, PARTICLE DISPERSION, PARTICLE-DISPERSED RESIN COMPOSITION, AND METHOD FOR PRODUCING ORGANIC-INORGANIC COMPOSITE PARTICLES TOHOKU UNIVERSITY (JP) 2011-10-13 US disclosed
EP-1862329-A1 Ink jet recording material and method of producing ink jet recording material OJI PAPER CO., LTD. (JP) 2007-12-05 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
CN-1891764-A Composite fine particles, dispersion, method of producing dispersion, ink jet recording material, and method of producing ink jet recording material OJI PAPER CO (JP) 2007-01-10 CN disclosed
US-20070003716-A1 Composite fine particles, dispersion, method of producing dispersion, ink jet recording material, and method of producing ink jet recording material OJI PAPER CO., LTD. (JP) 2007-01-04 US disclosed
EP-1739136-A1 Composite fine particles and ink jet recording material containing these particles. OJI PAPER CO., LTD. (JP) 2007-01-03 EP disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
WO-2004091522-A2 METHOD FOR TREATING NEURODEGENERATIVE DISORDERS MYRIAD GENETICS, INC. (US) 2004-10-28 WO disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed
EP-0444924-B1 Fused 7-membered cyclic compound and antipsychotic preparation containing the same SUNTORY LTD (JP) 1996-01-03 EP disclosed
US-5312625-A Fused 7-membered cyclic compound and antipsychotic preparation containing the same SUNTORY LIMITED (JP) 1994-05-17 US disclosed
EP-0444924-A1 Fused 7-membered cyclic compound and antipsychotic preparation containing the same SUNTORY LIMITED (JP) 1991-09-04 EP disclosed
EP-0120411-B1 SCORCH-INHIBITED ELASTOMERIC COMPOSITION NIPPON ZEON CO., LTD. (JP) 1987-02-04 EP disclosed
US-4569958-A BLEND OF HALOGEN CONTAINING ELASTOMER, DI-OR TRI-THIOL-S-TRIAZINE,AND POLYCARBOXYLIC ACID NIPPON ZEON CO LTD (JP) 1986-02-11 US disclosed
EP-0120411-A1 Scorch-inhibited elastomeric composition NIPPON ZEON CO., LTD. (JP) 1984-10-03 EP disclosed