Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517875 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| SCHEMBL21055951 | 0.90 | ALDH1A1 (0.50) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| SCHEMBL1344994 | 0.86 | PTGS2 (0.46) | ALDH1A1ALOX15MAPTPTGS2CXCL8 | |
| SCHEMBL9715714 | 0.86 | ALDH1A1 (0.47) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| Hydrogen Peroxide SCHEMBL9514730 | 0.85 | ALDH1A1 (0.59) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| SCHEMBL254364 | 0.85 | ALDH1A1 (0.59) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| SCHEMBL29657201 | 0.85 | ALDH1A1 (0.59) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| Benzene SCHEMBL28132022 | 0.85 | ALDH1A1 (0.59) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| SCHEMBL134091 | 0.85 | ALDH1A1 (0.59) | ALDH1A1ALOX15GAAKMT2ATDP1 | |
| SCHEMBL2204495 | 0.84 | PTGS2 (0.56) | ALDH1A1KMT2AMAPTPTGS2CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004091522-A2 | METHOD FOR TREATING NEURODEGENERATIVE DISORDERS | MYRIAD GENETICS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |