Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22578383 | 1.00 | HRH3 (0.40) | HRH3POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL22370887 | 1.00 | HRH3 (0.40) | HRH3POLBL3MBTL1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL29654932 | 0.98 | ALDH1A1 (0.40) | HRH3POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL13188860 | 0.95 | L3MBTL1 (0.44) | HRH3POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL25184347 | 0.95 | L3MBTL1 (0.44) | HRH3POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL13004066 | 0.86 | CHRM2 (0.43) | HRH3POLBL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL25433071 | 0.85 | DPP4 (0.38) | HRH3POLBL3MBTL1ALDH1A1 | |
| SCHEMBL12506853 | 0.83 | ALDH1A1 (0.45) | L3MBTL1MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL5612256 | 0.81 | DPP4 (0.41) | HRH3POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL12413684 | 0.81 | XPNPEP1 (0.42) | HRH3POLBL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086438-A1 | PRODRUGS OF NEUROSTEROID ANALOGS AND USES THEREOF | EMORY UNIVERSITY (US) | 2023-05-19 | — | — | WO | disclosed |