Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.36 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16872554 | 0.82 | LMNA (0.38) | KMT2ALMNAHTTCHRNA7HTR3A | |
| SCHEMBL25187820 | 0.82 | KMT2A (0.57) | KMT2APANK3LMNAHTTCHRNB4 | |
| SCHEMBL25186819 | 0.82 | PANK3 (0.48) | PANK3 | |
| SCHEMBL25265269 | 0.82 | PANK3 (0.48) | PANK3 | |
| SCHEMBL31104973 | 0.81 | MAP4K4 (0.44) | HSD11B1 | |
| SCHEMBL30427032 | 0.81 | MAP4K4 (0.44) | HSD11B1 | |
| SCHEMBL20929744 | 0.80 | KMT2A (0.41) | KMT2ASORDCHRNA7HTR3ACHRNB4 | |
| SCHEMBL26081837 | 0.80 | KMT2A (0.41) | KMT2ASORDCHRNA7HTR3ACHRNB4 | |
| SCHEMBL26087221 | 0.79 | HSD11B1 (0.41) | HSD11B1CHRM4CHRNA7 | |
| SCHEMBL25435546 | 0.77 | CHRM4 (0.38) | HSD11B1KMT2ACHRM4HCAR2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092098-A1 | HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |