Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | SMO | Q99835 | 7/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30427022 | 0.86 | HDAC1 (0.39) | CHRM4HSD11B1 | |
| SCHEMBL25197266 | 0.85 | SMO (0.43) | SMO | |
| SCHEMBL25189421 | 0.85 | SMO (0.43) | SMO | |
| SCHEMBL25193461 | 0.80 | HDAC1 (0.37) | CHRM4CHRM2 | |
| SCHEMBL21403160 | 0.78 | KDM4E (0.41) | — | |
| SCHEMBL30427037 | 0.77 | HDAC1 (0.51) | SMO | |
| SCHEMBL25181015 | 0.77 | HSD11B1 (0.39) | CHRM4HSD11B1HCAR2CHRNA7HTR3A | |
| SCHEMBL21403214 | 0.77 | SLC6A7 (0.36) | SMO | |
| SCHEMBL25187820 | 0.74 | KMT2A (0.57) | CHRNB4CHRNA3MEN1KMT2A | |
| SCHEMBL30459603 | 0.72 | BPTF (0.48) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092098-A1 | HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |