Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72471 | 0.92 | LMNA (0.62) | LMNAMAPTTSHRNOTUMHTT | |
| SCHEMBL31402602 | 0.89 | LMNA (0.60) | LMNAMAPTTSHRNOTUMHTT | |
| SCHEMBL13950724 | 0.88 | LMNA (0.55) | LMNAMAPTTSHRNOTUMKDM4E | |
| SCHEMBL28008922 | 0.88 | LMNA (0.50) | LMNAMAPTTSHRNOTUMKDM4E | |
| SCHEMBL3827098 | 0.86 | LMNA (0.57) | LMNAMAPTTSHRNOTUMKDM4E | |
| Hydrochloric Acid SCHEMBL15561414 | 0.84 | LMNA (0.61) | LMNAMAPTTSHRNOTUMKDM4E | |
| Butane SCHEMBL20558824 | 0.84 | LMNA (0.68) | LMNAMAPTTSHRNOTUMHTT | |
| SCHEMBL811107 | 0.82 | LMNA (0.54) | LMNAMAPTTSHRNOTUMHTT | |
| Ethylenediamine SCHEMBL7702427 | 0.82 | LMNA (0.54) | LMNAMAPTTSHRNOTUMKDM4E | |
| SCHEMBL1979159 | 0.82 | TSHR (0.65) | LMNAMAPTTSHRKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609107-B1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2024-12-11 | — | — | EP | disclosed |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2021-09-30 | — | — | US | disclosed |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2021-09-30 | — | — | US | disclosed |
| CN-103889999-B | Ion labeling for oligoribonucleotide synthesis | 皇家学习促进学会/麦吉尔大学 | 2021-06-01 | — | — | CN | disclosed |
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2021-05-25 | — | — | US | disclosed |
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2021-05-25 | — | — | US | disclosed |
| EP-2748176-B1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2019-04-17 | — | — | EP | disclosed |
| EP-2748176-B1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2019-04-17 | — | — | EP | disclosed |
| US-9920084-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-03-20 | — | — | US | disclosed |
| US-9920084-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-03-20 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| EP-2748176-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2014-07-02 | — | — | EP | disclosed |
| CN-103889999-A | Ionic tags for synthesis of oligoribonucleotides | UNIV MCGILL | 2014-06-25 | — | — | CN | disclosed |
| CN-103237805-A | Block synthesis of oligoribonucleotides | UNIV MCGILL | 2013-08-07 | — | — | CN | disclosed |
| EP-2609107-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2013-07-03 | — | — | EP | disclosed |
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | RNGTT, OSTC, DTYMK | LMNA 2711/4885MAPT 1176/4885TSHR 2662/4885 |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | RNGTT, OSTC, DTYMK | LMNA 2711/4885MAPT 1176/4885TSHR 2662/4885 |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | LMNA 2643/4885MAPT 1116/4885TSHR 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.