⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234461 | 0.83 | ALDH1A1 (0.58) | — | |
| SCHEMBL27660168 | 0.76 | ALDH1A1 (0.52) | — | |
| SCHEMBL27251960 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL24385153 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL10887099 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL712641 | 0.71 | — | — | |
| SCHEMBL13823021 | 0.69 | ALDH1A1 (0.58) | — | |
| SCHEMBL2005750 | 0.69 | CYP3A4 (0.56) | — | |
| SCHEMBL13181134 | 0.69 | — | — | |
| SCHEMBL10053525 | 0.69 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021955-A | Su Woleisheng midbody compounds and preparation method thereof | 上海奥博生物医药技术有限公司 | 2017-08-08 | — | — | CN | claimed |
| WO-2023082055-A1 | PHARMACEUTICAL COMPOSITION CONTAINING β-LACTAM COMPOUND AND USE THEREOF | 中国医学科学院医药生物技术研究所 | 2023-05-19 | — | — | WO | disclosed |
| CN-112480143-B | Beta-lactam derivatives, process for their preparation and their use, and intermediates and process for their preparation | 艾奇西(宜兴)新药研发有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115463219-A | Pharmaceutical composition containing beta-lactam compound and application thereof | 中国医学科学院医药生物技术研究所 | 2022-12-13 | — | — | CN | disclosed |
| CN-113975396-B | Pharmaceutical composition containing beta-lactam compound and application thereof | 中国医学科学院医药生物技术研究所 | 2022-11-29 | — | — | CN | disclosed |
| CN-113975396-A | Pharmaceutical composition containing beta-lactam compound and application thereof | 中国医学科学院医药生物技术研究所 | 2022-01-28 | — | — | CN | disclosed |
| CN-112480143-A | Beta-lactam derivative, preparation method and application thereof, and preparation method of intermediate and intermediate thereof | 广州艾奇西医药科技有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-108463461-A | Cephem compounds, its preparation and use | 奈加-RGM制药有限公司 | 2018-08-28 | — | — | CN | disclosed |
| CN-104961670-B | A kind of preparation method of the disubstituted ketimide derivative of N, O | 中国计量学院 | 2018-01-23 | — | — | CN | disclosed |
| CN-107021955-A | Su Woleisheng midbody compounds and preparation method thereof | 上海奥博生物医药技术有限公司 | 2017-08-08 | — | — | CN | disclosed |