Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.42 |
| ▸ | KDM6B | O15054 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 3/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31132807 | 1.00 | KDM4C (0.42) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| Propionic Acid SCHEMBL29088348 | 0.85 | TDP1 (0.39) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| Benzoic Acid SCHEMBL29088369 | 0.85 | KDM4C (0.39) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL31094071 | 0.81 | BACE1 (0.49) | MEN1ALDH1A1KMT2ABACE1 | |
| SCHEMBL6673753 | 0.81 | BACE1 (0.49) | MEN1ALDH1A1KMT2ABACE1 | |
| SCHEMBL1028187 | 0.79 | KDM4C (0.49) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL8528756 | 0.78 | BACE1 (0.40) | KDM4CKDM6BKDM4DMEN1ALDH1A1 | |
| SCHEMBL23199149 | 0.77 | HDAC1 (0.40) | TDP1BACE1 | |
| SCHEMBL15286291 | 0.76 | BACE1 (0.38) | KDM4CKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL14659892 | 0.76 | AOC1 (0.37) | KDM4EALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226914-A2 | MRGPRX2 ANTAGONISTS AND METHODS OF USE THEREOF | SEPTERNA, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-116472268-A | Compounds capable of binding to proteins and conjugates obtained from these compounds | MC SAF公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4181964-A1 | COMPOUNDS CAPABLE OF BINDING TO PROTEINS AND CONJUGATES OBTAINED FROM THESE COMPOUNDS | Mc SAF (FR) | 2023-05-24 | — | — | EP | disclosed |
| CN-114173825-A | Antibody-drug conjugates and their use in therapy | MCSAF公司 | 2022-03-11 | — | — | CN | disclosed |