Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.34 |
| ▸ | KDM6B | O15054 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29088369 | 0.87 | KDM4C (0.39) | TDP1SIRT3BACE1KDM4CKDM6B | |
| SCHEMBL25192580 | 0.85 | KDM4C (0.42) | TDP1BACE1KDM4CKDM6BKDM4E | |
| SCHEMBL31132807 | 0.85 | KDM4C (0.42) | TDP1BACE1KDM4CKDM6BKDM4E | |
| SCHEMBL12544235 | 0.75 | TDP1 (0.50) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL8594489 | 0.74 | TDP1 (0.56) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL14659892 | 0.74 | AOC1 (0.37) | BACE1KDM4EALDH1A1GLAGAA | |
| SCHEMBL5471663 | 0.73 | AOC1 (0.36) | BACE1 | |
| SCHEMBL8528756 | 0.72 | BACE1 (0.40) | TDP1BACE1KDM4CKDM6BALDH1A1 | |
| SCHEMBL23199149 | 0.72 | HDAC1 (0.40) | TDP1SIRT3BACE1 | |
| SCHEMBL11290152 | 0.72 | TDP1 (0.49) | TDP1SIRT3KDM4CKDM6BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472268-A | Compounds capable of binding to proteins and conjugates obtained from these compounds | MC SAF公司 | 2023-07-21 | — | — | CN | disclosed |