Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806754 | 0.84 | TP53 (0.42) | BACE1KMT2AMEN1TDP1LMNA | |
| Benzoic Acid SCHEMBL29088369 | 0.80 | KDM4C (0.39) | BACE1KMT2AMEN1KDM6BKDM5B | |
| SCHEMBL25192580 | 0.78 | KDM4C (0.42) | BACE1KMT2AMEN1KDM6BTDP1 | |
| SCHEMBL31132807 | 0.78 | KDM4C (0.42) | BACE1KMT2AMEN1KDM6BTDP1 | |
| SCHEMBL31094071 | 0.76 | BACE1 (0.49) | BACE1KMT2AMEN1LMNARAB9A | |
| SCHEMBL6673753 | 0.76 | BACE1 (0.49) | BACE1KMT2AMEN1LMNARAB9A | |
| SCHEMBL507447 | 0.73 | TDP1 (0.46) | KMT2ATDP1LMNAGALR3RAB9A | |
| SCHEMBL8530944 | 0.72 | SMN1; SMN2 (0.40) | BACE1KMT2AMEN1LMNAALDH1A1 | |
| Propionic Acid SCHEMBL29088348 | 0.72 | TDP1 (0.39) | BACE1KMT2AMEN1KDM6BTDP1 | |
| SCHEMBL21229106 | 0.72 | PPARG (0.39) | BACE1KMT2AELANELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849922-A | Preparation of substituted alkenoic acids | ELI LILLY AND COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5849766-A | Carbamoyl substituted heterocycles | ELI LILLY AND COMPANY (US) | 1998-12-15 | — | — | US | disclosed |