SCHEMBL25193686

SCHEMBL25193686

O=C(/C=C/c1ccc(OCCN2CCOCC2)cc1)c1ccc(OC(=O)C2CCCC2)cc1O

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 15/20 0.67
▸ BCHE P06276 4/20 0.59
▸ ACHE P22303 4/20 0.59
▸ MAOA P21397 1/20 0.54
▸ KEAP1 Q14145 1/20 0.49
▸ NFE2L2 Q16236 1/20 0.49
▸ APP P05067 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32662717 1.00 MAOB (0.67) MAOBBCHEACHEMAOAKEAP1
SCHEMBL25209703 0.86 MAOB (0.76) MAOBBCHEACHEMAOAKEAP1
SCHEMBL28695564 0.82 MAOB (0.71) MAOBBCHEACHEMAOAKEAP1
SCHEMBL29416705 0.82 MAOB (0.71) MAOBBCHEACHEMAOAKEAP1
SCHEMBL28684813 0.77 MAOB (0.71) MAOBBCHEACHEMAOAKEAP1
SCHEMBL29416758 0.77 MAOB (0.71) MAOBBCHEACHEMAOAKEAP1
SCHEMBL25197252 0.76 KEAP1 (0.72) MAOBKEAP1NFE2L2
SCHEMBL29416748 0.75 MAOB (0.60) MAOBBCHEACHEKEAP1NFE2L2
SCHEMBL28685577 0.75 MAOB (0.60) MAOBBCHEACHEKEAP1NFE2L2
SCHEMBL28703643 0.75 MAOB (0.86) MAOBBCHEACHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885BCHE 465/4885ACHE 656/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885BCHE 465/4885ACHE 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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