SCHEMBL2519451

SCHEMBL2519451

C=CC(=O)ON1CCCC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
TSHR P16473 3/20 0.34
BRD4 O60885 1/20 0.33
BRD2 P25440 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2325629 0.93 MITF (0.34) LMNAALDH1A1TP53HSD17B10KMT2A
SCHEMBL27336530 0.85 LMNA (0.38) LMNATSHRBRD4BRD2ALDH1A1
SCHEMBL3378465 0.81 LMNA (0.33) LMNATSHRBRD4BRD2
SCHEMBL9100870 0.78 BRD4 (0.32) LMNATSHRBRD4BRD2KMT2A
SCHEMBL353225 0.78 LMNA (0.42) LMNATSHRBRD4BRD2ALDH1A1
SCHEMBL28078795 0.78 LMNA (0.42) LMNATSHRBRD4BRD2ALDH1A1
SCHEMBL4006625 0.77 LMNA (0.37) LMNATSHRBRD4BRD2ALDH1A1
SCHEMBL2110295 0.77 LMNA (0.33) LMNATSHRBRD4BRD2CA12
SCHEMBL13966299 0.77 LMNA (0.31) LMNA
SCHEMBL11037068 0.76 LMNA (0.41) LMNATSHRBRD4BRD2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546298-B Non-fluorine polymer and treating agent 广东德美精细化工集团股份有限公司 2025-04-01 CN claimed
CN-118909187-A Non-fluorine polymer and surface treating agent 广东德美精细化工集团股份有限公司 2024-11-08 CN claimed
CN-118546298-A Non-fluorine polymer and treating agent 广东德美精细化工集团股份有限公司 2024-08-27 CN claimed
CN-114349922-B Flexible dual-cured resin composition and preparation method of molded body thereof 浙江华峰新材料有限公司 2024-01-23 CN claimed
CN-114853935-B Enhanced CO 2 Oil displacement additive capable of being mutually dissolved with crude oil and reducing crude oil viscosity and preparation method thereof 沧州中润化学助剂有限公司 2023-02-17 CN claimed
CN-114853935-A Enhanced CO 2 Oil displacement additive capable of being mutually dissolved with crude oil and reducing crude oil viscosity and preparation method thereof 沧州中润化学助剂有限公司 2022-08-05 CN claimed
CN-113121747-B Photosensitive resin and preparation method and application thereof 浙江华峰新材料有限公司 2022-08-02 CN claimed
CN-114349922-A Flexible dual-curing resin composition and preparation method of forming body thereof 浙江华峰新材料有限公司 2022-04-15 CN claimed
CN-113121747-A Photosensitive resin and preparation method and application thereof 浙江华峰新材料有限公司 2021-07-16 CN claimed
CN-112079954-B CO2 solubilized crude oil viscosity reducer and preparation method and application thereof 厦门大学 2021-05-25 CN claimed
CN-112079954-A CO (carbon monoxide)2Solubilized crude oil viscosity reducer and preparation method and application thereof 厦门大学 2020-12-15 CN claimed
CN-110078865-B High-temperature-resistant foaming agent and preparation method thereof 厦门大学 2020-07-17 CN claimed
CN-110078865-A A kind of high temperature resistant foaming agent and preparation method thereof 厦门大学 2019-08-02 CN claimed
US-20080274296-A1 ENERGY-CURABLE COATING/ADHESIVE COMPOSITIONS CONTAINING CHLORINATED POLYOLEFINS SCOTT LEVI F 2008-11-06 US claimed
US-20040228998-A1 Curable film preform compositions PERMATEX, INC. 2004-11-18 US claimed
WO-2004098472-A1 TRANSDERMAL DELIVERY SYSTEMS AND METHODS WATSON PHARMACEUTICALS, INC. (US) 2004-11-18 WO claimed
US-20040202704-A1 Transdermal delivery systems and methods WATSON PHARMACEUTICALS, INC. 2004-10-14 US claimed
EP-0557087-B1 Aqueous aerosol hair-spray compositions with a relatively low content of volatile organic compounds REVLON CONSUMER PROD CORP (US) 1995-12-06 EP claimed
CN-117568011-A CO (carbon monoxide) 2 Solubilizing viscosity reducer and preparation method and application thereof 中国石油大学(北京) 2024-02-20 CN disclosed
US-4760152-A Pyrrolidonyl acrylate block polymers GAF CORPORATION (US) 1988-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040202704-A1 Transdermal delivery systems and methods LPXN, GNRHR, TECR LMNA 960/4885TSHR 331/4885BRD4 4152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.