SCHEMBL3378465

SCHEMBL3378465

C=CC(=C)C(=O)ON1CCCC1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.32
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28078795 0.82 LMNA (0.42) LMNATSHRBRD4BRD2
SCHEMBL2519451 0.81 LMNA (0.36) LMNATSHRBRD4BRD2
SCHEMBL9100870 0.81 BRD4 (0.32) LMNATSHRBRD4BRD2
SCHEMBL4203179 0.79 KMT2A (0.40) LMNATSHRBRD4BRD2
SCHEMBL27433594 0.76 BRD4 (0.32) LMNABRD4BRD2
SCHEMBL3614121 0.75 LMNA (0.37) LMNATSHRBRD4BRD2
SCHEMBL2325629 0.75 MITF (0.34) LMNA
SCHEMBL5085961 0.75 BRD4 (0.39) LMNATSHRBRD4BRD2
SCHEMBL10583114 0.74 LMNA (0.35) LMNATSHR
SCHEMBL353225 0.74 LMNA (0.42) LMNATSHRBRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101039723-B Personal care compositions comprising visible beads, cationic polymer, and surfactant PROCTER & GAMBLE 2013-06-19 CN claimed
CN-1203840-C Cleaning composition PROCTER & GAMBLE (US) 2005-06-01 CN claimed
US-6699824-B1 RINSE-OFF LIQUID PERSONAL CLEANSING COMPOSITION COMPRISING WATER, WATER SOLUBLE SURFACTANT, WATER INSOLUBLE OIL SELECTED FROM HIGHLY BRANCHED POLYALPHAOLEFINS, SELECTED HYDROPHOBIC SKIN ACTIVE COMPONENT THE PROCTER & GAMBLE COMPANY 2004-03-02 US claimed
US-20020128162-A1 CLEANSING COMPOSITIONS PROCTER & GAMBLE COMPANY, THE 2002-09-12 US claimed
US-6444629-B1 RINSE-OFF PERSONAL CLEANSING COMPOSITION COMPRISING CRYSTALLIZING ANIONIC SURFACTANT, SECOND, DIFFERENT SURFACTANT, WATER INSOLUBLE OIL, PETROLATUM AND MINERAL OIL, AND WATER THE PROCTER & GAMBLE COMPANY 2002-09-03 US claimed
EP-1011625-B1 CLEANSING COMPOSITIONS PROCTER & GAMBLE (US) 2002-08-14 EP claimed
CN-1341012-A Cleaning composition PROCTER & GAMBLE (US) 2002-03-20 CN claimed
CN-1080557-C Cleansing compositions PROCTER & GAMBLE (US) 2002-03-13 CN claimed
EP-1156779-A1 CLEANSING COMPOSITIONS The Procter & Gamble Company (US) 2001-11-28 EP claimed
US-6312678-B1 SURFACTANT FOR PERSONAL CLEANING COMPOUND THE PROCTER & GAMBLE COMPANY 2001-11-06 US claimed
WO-1999009947-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009951-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009949-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009950-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009946-A1 CLEANSING COMPOSITIONS BASED ON HYDROPHOBICALLY MODIFIED SILICONES THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
WO-1999009948-A1 CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-03-04 WO claimed
EP-0197649-B1 LIQUID CLEANSING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1990-05-30 EP claimed
US-4678606-A Liquid cleansing composition THE PROCTER & GAMBLE COMPANY (US) 1987-07-07 US claimed
EP-0197649-A2 Liquid cleansing composition THE PROCTER & GAMBLE COMPANY (US) 1986-10-15 EP claimed
US-4438095-A New cosmetic compositions for hair or skin conditioning, and the application thereof SOCIETE ANONYME DITE: L'OREAL (FR) 1984-03-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128162-A1 CLEANSING COMPOSITIONS DEGS1, CUTA, CCR1 LMNA 895/4885TSHR 4457/4885BRD4 3522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.