Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170888 | 0.78 | CYP2A6 (0.47) | CYP2A6CYP1A2GPR3ALDH1A1HSD17B10 | |
| SCHEMBL637928 | 0.77 | CYP2A6 (0.50) | CYP2A6CYP1A2GPR3ALDH1A1HSD17B10 | |
| SCHEMBL9218101 | 0.77 | CYP2A6 (0.50) | CYP2A6CYP1A2GPR3ALDH1A1HSD17B10 | |
| SCHEMBL30133425 | 0.77 | ALDH1A1 (0.42) | CYP2A6CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL29751038 | 0.77 | ALDH1A1 (0.42) | CYP2A6CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL901849 | 0.77 | ALDH1A1 (0.42) | CYP2A6CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL31583095 | 0.77 | CYP1A2 (0.42) | CYP2A6CYP1A2ALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL9433849 | 0.77 | CYP2A6 (0.45) | CYP2A6CYP1A2GPR3ALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL13730044 | 0.76 | CYP2A6 (0.48) | CYP2A6CYP1A2GPR3ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28363251 | 0.76 | MAPT (0.50) | CYP2A6CYP1A2GPR3ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119033-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20240300951-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-09-12 | — | — | US | disclosed |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-08-15 | — | — | US | disclosed |
| EP-4380936-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BeiGene, Ltd. (KY) | 2024-06-12 | — | — | EP | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023011456-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BEIGENE, LTD. (KY) | 2023-02-09 | — | — | WO | disclosed |
| CN-109153645-A | Process for preparing 6-alkynyl-pyridine derivatives | 勃林格殷格翰国际有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108341777-A | Compound of isobioquin group and its application | 四川科伦博泰生物医药股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-102639529-B | Isoxazoline derivative-based pesticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-19 | — | — | CN | disclosed |
| CN-101454288-B | Benzofluoranthene compound and organic light-emitting device using the same | CANON KK | 2012-12-12 | — | — | CN | disclosed |
| US-8034944-B2 | Benzofluoranthene compound and organic light-emitting device using the compound | CANON KABUSHIKI KAISHA (JP) | 2011-10-11 | — | — | US | disclosed |
| US-20090278118-A1 | BENZOFLUORANTHENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2009-11-12 | — | — | US | disclosed |
| CN-101454288-A | Benzofluoranthene compound and organic light-emitting device using the same | CANON KK (JP) | 2009-06-10 | — | — | CN | disclosed |
| WO-2008078824-A1 | BENZOFLUORANTHENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300951-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | CYP2A6 3696/4885CYP1A2 2016/4885GPR3 2325/4885 |
| US-20090278118-A1 | BENZOFLUORANTHENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | XDH, XPO6, PAX3 | CYP2A6 158/4885CYP1A2 96/4885GPR3 1673/4885 |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | CYP2A6 3696/4885CYP1A2 2016/4885GPR3 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.