SCHEMBL2519601

SCHEMBL2519601

C=Cc1ccccc1C=C.OCc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
CYP1A2 P05177 1/20 0.54
PTGS1 P23219 1/20 0.54
SLC6A2 P23975 1/20 0.54
CYP2C19 P33261 1/20 0.54
PTGS2 P35354 1/20 0.54
SLC6A3 Q01959 1/20 0.54
HIF1A Q16665 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
LTA4H P09960 2/20 0.54
EPHX2 P34913 1/20 0.54
MAOB P27338 6/20 0.50
BCHE P06276 1/20 0.50
FFAR1 O14842 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
MAOA P21397 2/20 0.49
GAA P10253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126452 0.87 LMNA (0.70) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL20855968 0.84 CYSLTR1 (0.44) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8344663 0.82 MAPT (0.51) LMNACYP1A2CYP2C19GAAMAPT
SCHEMBL6192316 0.82 LMNA (0.63) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL1746578 0.82 LTA4H (0.71) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL5400014 0.81 APP (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL3241768 0.80 NPC1 (0.47) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL23440397 0.79 LMNA (0.59) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL1029072 0.76 CCNB2 (0.62) CYP1A2CYP2C19LTA4HGAAMAPT
SCHEMBL763259 0.76 LMNA (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9810658-B2 Method for the detection and quantification of analytes using three-dimensional paper-based devices BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-11-07 US disclosed
US-20150355132-A1 METHOD FOR THE DETECTION AND QUANTIFICATION OF ANALYTES USING THREE-DIMENSIONAL PAPER-BASED DEVICES BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2015-12-10 US disclosed
EP-2839296-A1 METHOD FOR THE DETECTION AND QUANTIFICATION OF ANALYTES USING THREE-DIMENSIONAL PAPER-BASED DEVICES Board Of Regents, The University Of Texas System (US) 2015-02-25 EP disclosed
WO-2013158827-A9 METHOD FOR THE DETECTION AND QUANTIFICATION OF ANALYTES USING THREE-DIMENSIONAL PAPER-BASED DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-01-03 WO disclosed
US-8580845-B2 Functionalized expanded porphyrins BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-11-12 US disclosed
WO-2013158827-A1 METHOD FOR THE DETECTION AND QUANTIFICATION OF ANALYTES USING THREE-DIMENSIONAL PAPER-BASED DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-10-24 WO disclosed
US-8257967-B2 Development of a sensor array system capable of discriminating mixtures of cardiovascular risk factor analytes for the prediction of coronary heart disease BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-09-04 US disclosed
US-20120135396-A1 Multi-Shell Microspheres With Integrated Chromatographic And Detection Layers For Use In Array Sensors BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-05-31 US disclosed
US-20110251075-A1 SYSTEM AND METHOD FOR THE ANALYSIS OF BODILY FLUIDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-10-13 US disclosed
EP-2230314-A1 Method of sensing an analyte The Board of Regents,The University of Texas System (US) 2010-09-22 EP disclosed
US-20040029259-A1 Method and system for the detection of cardiac risk factors NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-02-12 US disclosed
US-6680206-B1 Sensor arrays for the measurement and identification of multiple analytes in solutions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2004-01-20 US disclosed
US-6649403-B1 Placing particle in a cavity using automated dispenser; covering so that a channel is formed for fluid flow; signals; use for detection of analytes, toxins, and/or bacteria in medical, food/beverage, and environmental solutions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS 2003-11-18 US disclosed
US-20030186228-A1 Apparatus for high speed characterization and discrimination of toxins and/or bacteria in medical, food/beverage and environmental solutions THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2003-10-02 US disclosed
US-6602702-B1 Rapid characterization of multi-analyte fluids using a light source, sensor array, and a detector; signals; use for discriminating mixtures of analytes, toxins, and/or bacteria in medical, food/beverage, and environmental solutions THE UNIVERSITY OF TEXAS SYSTEM 2003-08-05 US disclosed
US-6589779-B1 Light sources; sensor arrays; detectors; cavities; particles; use for rapid discrimination of mixtures of analytes, toxins, and/or bacteria in medical, food/beverage, and environmental solutions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2003-07-08 US disclosed
US-20030064422-A1 Method and system for collecting and transmitting chemical information NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2003-04-03 US disclosed
US-20020197622-A1 Method and apparatus for the confinement of materials in a micromachined chemical sensor array NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-12-26 US disclosed
US-20020160363-A1 Magnetic-based placement and retention of sensor elements in a sensor array BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-10-31 US disclosed
US-20020045272-A1 Method and apparatus for the delivery of samples to a chemical sensor array NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-04-18 US disclosed