SCHEMBL25196752

SCHEMBL25196752

O=C(C=Cc1ccc(O)cc1)c1ccc(N2CCCC2=O)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.66
CTSB P07858 2/20 0.66
F3 P13726 3/20 0.59
ALDH1A1 P00352 4/20 0.57
MAPT P10636 5/20 0.52
RAB9A P51151 4/20 0.52
MAOB P27338 3/20 0.52
MAOA P21397 2/20 0.52
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
CXCL12 P48061 1/20 0.52
POLB P06746 1/20 0.52
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
CYP3A4 P08684 2/20 0.51
HSPD1 P10809 2/20 0.51
HSPE1 P61604 2/20 0.51
CYP1B1 Q16678 2/20 0.51
PKM P14618 1/20 0.51
NFKB1 P19838 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25196799 1.00 CTSL (0.66) CTSLCTSBF3ALDH1A1MAPT
SCHEMBL25191350 0.91 ALDH1A1 (0.71) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL25195117 0.91 ALDH1A1 (0.71) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL31233022 0.85 MAPT (0.63) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL30383840 0.85 MAPT (0.63) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL25204031 0.85 MAPT (0.63) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL25192707 0.85 MAPT (0.63) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL25198029 0.83 ALDH1A1 (0.50) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL25207094 0.83 MKNK2 (0.55) CTSLCTSBALDH1A1MAPTRAB9A
SCHEMBL25196904 0.83 ALDH1A1 (0.50) CTSLCTSBALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885CTSB 60/4885F3 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.