SCHEMBL25197853

SCHEMBL25197853

O=C(/C=C/c1cccc(O)c1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.75

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
P4HB P07237 4/20 0.75
CYP1A1 P04798 8/20 0.71
CYP1B1 Q16678 8/20 0.71
MAOB P27338 5/20 0.71
CXCL12 P48061 1/20 0.63
NPC1 O15118 1/20 0.56
MAPT P10636 1/20 0.56
RAB9A P51151 1/20 0.56
CYP1A2 P05177 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384485 1.00 P4HB (0.75) P4HBCYP1A1CYP1B1MAOBCXCL12
SCHEMBL30384167 1.00 P4HB (0.75) P4HBCYP1A1CYP1B1MAOBCXCL12
SCHEMBL25211692 1.00 P4HB (0.75) P4HBCYP1A1CYP1B1MAOBCXCL12
SCHEMBL30383170 0.86 P4HB (0.59) P4HBCYP1A1CYP1B1MAOBNPC1
SCHEMBL25198976 0.86 P4HB (0.59) P4HBCYP1A1CYP1B1MAOBNPC1
SCHEMBL8233699 0.86 P4HB (0.69) P4HBCYP1A1CYP1B1MAOBCYP1A2
SCHEMBL25199747 0.86 P4HB (1.00) P4HBCYP1A1CYP1B1MAOBMAPT
SCHEMBL25221835 0.86 P4HB (1.00) P4HBCYP1A1CYP1B1MAOBMAPT
SCHEMBL25266214 0.86 P4HB (0.59) P4HBCYP1A1CYP1B1MAOBNPC1
SCHEMBL8233695 0.86 P4HB (0.69) P4HBCYP1A1CYP1B1MAOBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B P4HB 552/4885CYP1A1 696/4885CYP1B1 230/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885CYP1A1 1747/4885CYP1B1 1027/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885CYP1A1 1747/4885CYP1B1 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.