Properidine

Properidine

SCHEMBL25199

CC(C)OC(=O)C1(c2ccccc2)CCN(C)CC1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.68
OPRD1 P41143 4/20 0.68
OPRK1 P41145 4/20 0.68
SLC22A1 O15245 1/20 0.68
SLC6A4 P31645 1/20 0.68
ADRA1A P35348 1/20 0.68
KCNH2 Q12809 1/20 0.68
CHRM5 P08912 2/20 0.54
CHRM1 P11229 2/20 0.54
CHRM3 P20309 2/20 0.54
KCNA3 P22001 1/20 0.50
APOBEC3A P31941 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977360 0.87 APOBEC3A (0.57) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL14534189 0.84 OPRM1 (0.71) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Meperidine SCHEMBL25431 0.81 OPRM1 (1.00) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL28765681 0.80 OPRM1 (0.65) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL3046108 0.80 OPRM1 (0.65) OPRM1OPRD1OPRK1SLC22A1SLC6A4
SCHEMBL3255785 0.80 OPRM1 (0.67) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Meperidine SCHEMBL194412 0.79 OPRM1 (1.00) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Meperidine SCHEMBL2860723 0.79 OPRM1 (1.00) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Meperidine SCHEMBL1083668 0.79 OPRM1 (1.00) OPRM1OPRD1OPRK1SLC22A1SLC6A4
Meperidine SCHEMBL28905219 0.79 OPRM1 (0.97) OPRM1OPRD1OPRK1SLC22A1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5931 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
WO-2025053315-A1 METHOD FOR RECOVERING AND REMOVING PALLADIUM IN PREPARATION OF ANTICANCER AGENT PRODRUG CONJUGATE 파로스젠 주식회사 2025-03-13 WO claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-12036192-B2 Combination treatments for opioid crisis PRESTI MICHAEL (US) 2024-07-16 US claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
EP-0731694-A4 1996-10-02 EP claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed