SCHEMBL25199019

SCHEMBL25199019

O=C(O)CNS(=O)(=O)c1ccc(C(=O)/C=C/c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 2/20 0.58
MMP1 P03956 2/20 0.50
GAA P10253 1/20 0.50
MMP12 P39900 1/20 0.50
XDH P47989 1/20 0.50
MAOB P27338 1/20 0.49
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
ALOX15 P16050 1/20 0.48
MAPK1 P28482 1/20 0.48
BLM P54132 1/20 0.48
CASP7 P55210 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MMP2 P08253 1/20 0.48
MMP3 P08254 1/20 0.48
MMP7 P09237 1/20 0.48
MMP9 P14780 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25197345 0.90 MAOB (0.64) MEP1BMAOBMAPT
SCHEMBL25191771 0.90 MMP1 (0.63) MEP1BMMP1GAAMMP12MAOB
SCHEMBL25212824 0.87 MEP1B (0.60) MEP1BXDHMAOBTP53CYP3A4
SCHEMBL25199625 0.87 MEP1B (0.60) MEP1BXDHMAOBTP53CYP3A4
SCHEMBL25207415 0.87 MEP1B (0.60) MEP1BXDHMAOBTP53CYP3A4
SCHEMBL25190507 0.87 MAPT (0.57) GAACYP3A4MAPTSMN1; SMN2
SCHEMBL25209867 0.87 MAPT (0.57) GAACYP3A4MAPTSMN1; SMN2
SCHEMBL25202175 0.87 F3 (0.63) MEP1BXDHMAOBCYP3A4MAPT
SCHEMBL7671414 0.84 MEP1B (0.73) MEP1BMMP1GAAMMP12TDP1
SCHEMBL25197794 0.84 ABCG2 (0.49) MMP1MAOBMAPTBLMMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MEP1B 1065/4885MMP1 229/4885GAA 1372/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MEP1B 1104/4885MMP1 125/4885GAA 1183/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MEP1B 1104/4885MMP1 125/4885GAA 1183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.