Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 15/20 | 0.76 |
| ▸ | NOX1 | Q9Y5S8 | 10/20 | 0.76 |
| ▸ | CYBB | P04839 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25209324 | 0.90 | NOX4 (0.77) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL25197259 | 0.89 | NOX4 (0.62) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL25212704 | 0.89 | NOX4 (0.61) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL31260586 | 0.88 | NOX4 (0.78) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL25195809 | 0.88 | NOX4 (0.78) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL25192759 | 0.86 | NOX4 (0.61) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL24198362 | 0.86 | NOX4 (1.00) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL25198925 | 0.83 | NOX4 (0.60) | NOX4NOX1CYBBMEN1KMT2A | |
| SCHEMBL25200594 | 0.81 | NOX4 (0.76) | NOX4NOX1CYBB | |
| SCHEMBL25199884 | 0.77 | TDP1 (0.53) | NOX4NOX1CYBBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552779-B2 | 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases | DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2026-02-17 | — | — | US | disclosed |
| US-20240358679-A1 | PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES | INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (KR) | 2024-10-31 | — | — | US | disclosed |
| US-20230286956-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | KNU- INDUSTRY COOPERATION FOUNDATION (KR) | 2023-09-14 | — | — | US | disclosed |
| WO-2023132681-A1 | PHARMACEUTICAL COMPOSITION AND FOOD COMPOSITION COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND DERIVATIVE THEREOF FOR PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASE | 덕성여자대학교 산학협력단 | 2023-07-13 | — | — | WO | disclosed |
| EP-4183776-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | Duksung Women's University Industry-Academic Cooperation Foundation (KR) | 2023-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552779-B2 | 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases | SNCA, HTT, PSEN1 | NOX4 770/4885NOX1 240/4885CYBB 959/4885 |
| US-20230286956-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | PSEN2, PARK7, SNCA | NOX4 928/4885NOX1 858/4885CYBB 1464/4885 |
| US-20240358679-A1 | PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES | GPX4, GPX1, SELENOI | NOX4 2018/4885NOX1 1984/4885CYBB 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.