Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 10/20 | 0.44 |
| ▸ | CNR2 | P34972 | 9/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24208876 | 1.00 | OPRL1 (0.51) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL25265924 | 1.00 | OPRL1 (0.51) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL25509775 | 0.88 | OPRL1 (0.48) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL25517568 | 0.88 | OPRL1 (0.47) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL24208879 | 0.87 | OPRL1 (0.47) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL25212508 | 0.83 | OPRL1 (0.53) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL24208916 | 0.83 | OPRL1 (0.53) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL25212509 | 0.83 | OPRL1 (0.53) | OPRL1KCNH2CNR1CNR2 | |
| SCHEMBL25197522 | 0.79 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL24208900 | 0.79 | CNR1 (0.68) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | SHANGHAITECH UNIVERSITY (CN) | 2023-05-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | TIMP3, AFG3L2, MMP3 | OPRL1 3496/4885KCNH2 4695/4885CNR1 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.