Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.48 |
| ▸ | CES1 | P23141 | 10/20 | 0.48 |
| ▸ | CES2 | O00748 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120075 | 0.93 | FAAH (0.55) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28986780 | 0.93 | FAAH (0.55) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL969166 | 0.93 | FAAH (0.55) | FAAHCES1CES2MEN1CYP1A2 | |
| Ethylene Glycol SCHEMBL28018645 | 0.87 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL29072795 | 0.83 | FAAH (0.63) | FAAHCES1MEN1CYP1A2KMT2A | |
| SCHEMBL723655 | 0.83 | FAAH (0.63) | FAAHCES1MEN1CYP1A2KMT2A | |
| SCHEMBL11732585 | 0.77 | FAAH (0.55) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3777756 | 0.77 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3778978 | 0.77 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9435633 | 0.77 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083315-A1 | NCOVSIRNA DRUG FOR TARGETED DELIVERY OF SHRNA BY USING RBD, SYNTHESIS METHOD THEREFOR AND USE THEREOF | 翁炳焕 | 2023-05-19 | — | — | WO | disclosed |
| CN-114870026-A | Preparation method of ACE2siRNA medicine for targeting delivery of shRNA by ACE2 | 杭州痴创生物科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114832100-A | Preparation method of nCOVsiRNA medicine for delivering shRNA in RBD targeting manner | 杭州痴创生物科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114617977-A | ACE2siRNA medicine for targeting delivery of shRNA by ACE2 | 杭州痴创生物科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114569712-A | nCOVsiRNA medicine for delivering shRNA in RBD targeting manner | 杭州痴创生物科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114569737-A | Screening method of anti-variant strain conserved target nCOVsiRNA delivered by novel vector | 杭州痴创生物科技有限公司 | 2022-06-03 | — | — | CN | disclosed |