SCHEMBL25199631

SCHEMBL25199631

Cc1ccc(C(=O)/C=C/c2ccc(O)c(Cl)c2)cc1

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CXCL12 P48061 4/20 0.67
▸ MAOA P21397 5/20 0.66
▸ MAOB P27338 5/20 0.66
▸ MAPT P10636 4/20 0.66
▸ POLB P06746 1/20 0.63
▸ RAB9A P51151 1/20 0.63
▸ CXCR4 P61073 1/20 0.58
▸ PTGS2 P35354 1/20 0.57
▸ DHODH Q02127 1/20 0.57
▸ CYP1B1 Q16678 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ TERT O14746 1/20 0.56
▸ SNCA P37840 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382667 1.00 CXCL12 (0.67) CXCL12MAOAMAOBMAPTPOLB
SCHEMBL30384517 0.88 CXCL12 (0.80) CXCL12MAOAMAOBMAPTCXCR4
SCHEMBL25198501 0.88 BACE1 (0.68) CXCL12MAOAMAOBMAPTPOLB
SCHEMBL13869118 0.88 PTGS2 (0.72) CXCL12MAOAMAOBMAPTPOLB
SCHEMBL25209522 0.88 CXCL12 (0.80) CXCL12MAOAMAOBMAPTCXCR4
SCHEMBL25221567 0.88 CXCL12 (0.80) CXCL12MAOAMAOBMAPTCXCR4
SCHEMBL25200404 0.88 BACE1 (0.68) CXCL12MAOAMAOBMAPTPOLB
SCHEMBL30383358 0.88 BACE1 (0.68) CXCL12MAOAMAOBMAPTPOLB
SCHEMBL25265529 0.86 MAPT (0.76) CXCL12MAOAMAOBMAPTPOLB
SCHEMBL23951571 0.86 MAPT (0.76) CXCL12MAOAMAOBMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CXCL12 399/4885MAOA 1902/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CXCL12 287/4885MAOA 3145/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CXCL12 287/4885MAOA 3145/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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