SCHEMBL25199681

SCHEMBL25199681

O=C(O)CCCOc1ccc(C(=O)/C=C/c2ccc(Cl)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 5/20 0.68
▸ ABCG2 Q9UNQ0 3/20 0.62
▸ MAOA P21397 1/20 0.61
▸ CYSLTR2 Q9NS75 1/20 0.61
▸ CYSLTR1 Q9Y271 2/20 0.58
▸ CYP1B1 Q16678 1/20 0.57
▸ BCHE P06276 1/20 0.56
▸ ACHE P22303 1/20 0.56
▸ CXCL12 P48061 1/20 0.56
▸ PPARA Q07869 2/20 0.56
▸ HRH3 Q9Y5N1 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25197151 0.94 MAOB (0.70) MAOBABCG2MAOACYSLTR2CYSLTR1
SCHEMBL11461543 0.90 ABCG2 (0.62) MAOBABCG2MAOABCHEACHE
SCHEMBL25198610 0.90 ABCG2 (0.62) MAOBABCG2MAOABCHEACHE
SCHEMBL25193715 0.88 BCHE (0.70) MAOBMAOABCHEACHEPPARA
SCHEMBL25193666 0.87 MAOB (0.71) MAOBABCG2MAOACYP1B1
SCHEMBL25212572 0.87 MAOB (0.68) MAOBABCG2MAOACYP1B1BCHE
SCHEMBL25230131 0.87 MAOB (0.70) MAOBABCG2MAOACYP1B1BCHE
SCHEMBL25218068 0.87 MAOB (0.68) MAOBABCG2MAOACYP1B1BCHE
SCHEMBL25219612 0.87 MAOB (0.70) MAOBABCG2MAOACYP1B1BCHE
SCHEMBL29014213 0.86 MAOB (0.70) MAOBABCG2MAOACYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885ABCG2 1606/4885MAOA 1902/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885MAOA 3145/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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