SCHEMBL25230131

SCHEMBL25230131

COc1ccc(/C=C/C(=O)c2ccc(OCCCC(=O)O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 7/20 0.70
▸ F3 P13726 2/20 0.69
▸ XDH P47989 2/20 0.67
▸ MAPT P10636 4/20 0.64
▸ MEN1 O00255 2/20 0.64
▸ ALDH1A1 P00352 2/20 0.64
▸ KMT2A Q03164 2/20 0.64
▸ BCHE P06276 2/20 0.64
▸ HSPD1 P10809 1/20 0.64
▸ TNFRSF1A P19438 1/20 0.64
▸ HSPE1 P61604 1/20 0.64
▸ CYP1B1 Q16678 1/20 0.64
▸ CYP3A4 P08684 1/20 0.64
▸ NFKB1 P19838 1/20 0.64
▸ NFKB2 Q00653 1/20 0.64
▸ RELA Q04206 1/20 0.64
▸ ABCG2 Q9UNQ0 2/20 0.63
▸ MAOA P21397 3/20 0.63
▸ P4HB P07237 1/20 0.63
▸ CALM1 P0DP23 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25188984 0.94 MAOB (0.71) MAOBF3XDHMAPTMEN1
SCHEMBL25233397 0.90 MAPT (0.66) MAOBF3MAPTKMT2ABCHE
SCHEMBL25193666 0.90 MAOB (0.71) MAOBMAPTALDH1A1KMT2ACYP1B1
SCHEMBL25219612 0.90 MAOB (0.70) MAOBMAPTALDH1A1KMT2ABCHE
SCHEMBL11461543 0.90 ABCG2 (0.62) MAOBXDHMAPTKMT2ABCHE
SCHEMBL25198610 0.90 ABCG2 (0.62) MAOBXDHMAPTKMT2ABCHE
SCHEMBL25193715 0.88 BCHE (0.70) MAOBBCHEMAOAACHE
SCHEMBL25199681 0.87 MAOB (0.68) MAOBBCHECYP1B1ABCG2MAOA
SCHEMBL25212572 0.87 MAOB (0.68) MAOBMAPTKMT2ABCHETNFRSF1A
SCHEMBL25218068 0.87 MAOB (0.68) MAOBMAPTKMT2ABCHECYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885F3 5/4885XDH 1328/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885XDH 1963/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885XDH 1963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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