SCHEMBL25198610

SCHEMBL25198610

O=C(O)CCCOc1ccc(C(=O)/C=C/c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 2/20 0.62
▸ XDH P47989 1/20 0.62
▸ BCHE P06276 9/20 0.58
▸ ACHE P22303 8/20 0.58
▸ PPARA Q07869 2/20 0.58
▸ HRH3 Q9Y5N1 1/20 0.57
▸ MAOA P21397 1/20 0.56
▸ MAOB P27338 1/20 0.56
▸ NPC1 O15118 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ RAB9A P51151 1/20 0.56
▸ KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11461543 1.00 ABCG2 (0.62) ABCG2XDHBCHEACHEPPARA
SCHEMBL25193715 0.90 BCHE (0.70) BCHEACHEPPARAMAOAMAOB
SCHEMBL25218068 0.90 MAOB (0.68) ABCG2BCHEACHEPPARAHRH3
SCHEMBL25212572 0.90 MAOB (0.68) ABCG2BCHEACHEPPARAHRH3
SCHEMBL25230131 0.90 MAOB (0.70) ABCG2XDHBCHEACHEMAOA
SCHEMBL25219612 0.90 MAOB (0.70) ABCG2BCHEACHEPPARAMAOA
SCHEMBL25193666 0.90 MAOB (0.71) ABCG2MAOAMAOBNPC1MAPT
SCHEMBL25199681 0.90 MAOB (0.68) ABCG2BCHEACHEPPARAHRH3
SCHEMBL25233397 0.87 MAPT (0.66) ABCG2BCHEACHEPPARAMAOA
SCHEMBL25216496 0.86 PPARA (0.74) BCHEACHEPPARAMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885XDH 1328/4885BCHE 588/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885XDH 1963/4885BCHE 465/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885XDH 1963/4885BCHE 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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